The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.a

Left or biventricular dysfunction/failure

Publications

Inui T, Kohno H, Matsuura K, Ueda H, Tamura Y, Watanabe M, Inage Y, Yakita Y, Matsumiya G

A case of left ventricular assist device application for chemotherapy-related cardiomyopathy caused by trastuzumab and anthracycline.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2020 Sep;23;270-274 — 2020 Sep — 270-274

Yuki D, Okura Y, Takayama T, Kawasaki T, Kanbayashi C, Sato N

A case of chemoradiotherapy-associated cardiotoxicity that developed into acute heart failure with progressive subendocardial fibrosis.

Journal of cardiology cases 2014 Sep;10;115-120 — 2014 Sep — 115-120