The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.e

Path: Acute fibrinous organizing pneumonia (AFOP-pattern) (see also If)

Publications

Naraoka T, Sumi T, Keira Y, Nakata H, Chiba H

Epirubicin and Cyclophosphamide-induced Acute Fibrinous and Organizing Pneumonia.

American journal of respiratory and critical care medicine 2021 10 15;204;e92-e93 — 2021 10 15 — e92-e93

Gomes R, Padrão E, Dabó H, Soares Pires F, Mota P, Melo N, Jesus JM, Cunha R, Guimarães S, Souto Moura C, Morais A

Acute fibrinous and organizing pneumonia: A report of 13 cases in a tertiary university hospital.

Medicine 2016 Jul;95;e4073 — 2016 Jul — e4073