The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.ak

Cardiotoxicity

See under specific drugs or agents

Publications

Yuki D, Okura Y, Takayama T, Kawasaki T, Kanbayashi C, Sato N

A case of chemoradiotherapy-associated cardiotoxicity that developed into acute heart failure with progressive subendocardial fibrosis.

Journal of cardiology cases 2014 Sep;10;115-120 — 2014 Sep — 115-120

Mehta J, Nagler A, Schechter D, Rein AJ, Slavin S

Fatal acute cardiomyopathy associated with "non-cardiotoxic" chemotherapy for autologous bone marrow transplantation.

American journal of hematology 1992 Jul;40;242 — 1992 Jul — 242