The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.y

Pleuroparenchymal fibroelastosis (PPFE)

Publications

Baqir M, LeMahieu AM, Hartman TE, Farah WH, Yi EE, Ryu JH

Pleuroparenchymal fibroelastosis: review of 81 cases.

Expert review of respiratory medicine 2026 Feb;20 — 2026 Feb — 217-226

Rodrigues Vieira AC, Monteiro Ferra JR, Vicente De Carvalho JS, Melo N, Caetano Mota P, Novais E Bastos H, Pereira JM, Souto Moura C, Morais A

Pleuroparenchymal fibroelastosis as a complication of chemotherapy: A case report.

Molecular and clinical oncology 2022 Mar;16;71 — 2022 Mar — 71

Nguyen HN, Das S, Gazzaneo MC, Melicoff E, Mallory GB, Eldin KW, Guillerman RP

Clinico-radiologic features of pleuroparenchymal fibroelastosis in children.

Pediatric radiology 2019 Apr 19;; — 2019 Apr 19

Portillo K, Guasch I, Becker C, Andreo F, Fernández-Figueras MT, Ramirez Ruz J, Martinez-Barenys C, García-Reina S, Lopez de Castro P, Sansano I, Villar A, Ruiz-Manzano J

Pleuroparenchymal Fibroelastosis: A New Entity within the Spectrum of Rare Idiopathic Interstitial Pneumonias.

Case reports in pulmonology 2015;2015;810515 — 2015 — 810515

Chen F, Matsubara K, Miyagawa-Hayashino A, Tada K, Handa T, Yamada T, Sato M, Aoyama A, Date H

Lung transplantation for pleuroparenchymal fibroelastosis after chemotherapy.

The Annals of thoracic surgery 2014 Nov;98;e115-7 — 2014 Nov — e115-7

Camus P, von der Thüsen J, Hansell DM, Colby TV

Pleuroparenchymal fibroelastosis: one more walk on the wild side of drugs?

The European respiratory journal 2014 Aug;44;289-96 — 2014 Aug — 289-96

Beynat-Mouterde C, Beltramo G, Lezmi G, Pernet D, Camus C, Fanton A, Foucher P, Cottin V, Bonniaud P

Pleuroparenchymal fibroelastosis as a late complication of chemotherapy agents.

The European respiratory journal 2014 Aug;44;523-7 — 2014 Aug — 523-7

von der Thüsen JH

Pleuroparenchymal Fibroelastosis: Its Pathological Characteristics.

Current respiratory medicine reviews 2013 Aug;9;238-247 — 2013 Aug — 238-247

Frankel SK, Cool CD, Lynch DA, Brown KK

Idiopathic pleuroparenchymal fibroelastosis: description of a novel clinicopathologic entity.

Chest 2004 Dec;126;2007-13 — 2004 Dec — 2007-13