The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.g

Coronary artery disease (acute) - Myocardial ischemia/infarction

Publications

Kawano N, Yamaguchi K, Niki T, Yamamoto T, Iwase T, Taketani Y, Ise T, Yamada H, Soeki T, Wakatsuki T, Kawano K, Kakutani A, Sata M

Two cases of acute myocardial infarction during combined chemotherapy in young patients with testicular cancer.

Journal of cardiology cases. 2013;7(6):e176-e180

Tsibiribi P, Descotes J, Lombard-Bohas C, Barel C, Bui-Xuan B, Belkhiria M, Tabib A, Timour Q

Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease.

Bulletin du cancer. 2006;93(3):E27-30

Federman DG, Henry G

Chemotherapy-induced myocardial necrosis in a patient with chronic lymphocytic leukemia.

Respiratory medicine. 1997;91(9):565-7