The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Coronary artery disease (acute) - Myocardial ischemia/infarction
Publications
Kawano N, Yamaguchi K, Niki T, Yamamoto T, Iwase T, Taketani Y, Ise T, Yamada H, Soeki T, Wakatsuki T, Kawano K, Kakutani A, Sata M
Two cases of acute myocardial infarction during combined chemotherapy in young patients with testicular cancer.
Journal of cardiology cases 2013 Jun;7;e176-e180 — 2013 Jun — e176-e180
Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease.
Bulletin du cancer 2006 Mar 01;93;E27-30 — 2006 Mar 01 — E27-30
Chemotherapy-induced myocardial necrosis in a patient with chronic lymphocytic leukemia.
Respiratory medicine 1997 Oct;91;565-7 — 1997 Oct — 565-7