The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary arterial hypertension
Publications
Rapid development of pulmonary hypertension during treatment of paediatric cancer.
Cardiology in the young 2019 Mar;29;286-289 — 2019 Mar — 286-289
In situ thrombosis of small pulmonary arteries in pulmonary hypertension developing after chemotherapy for malignancy.
Pulmonary medicine 2015;2015;230846 — 2015 — 230846
Armstrong GT, Joshi VM, Zhu L, Srivastava D, Zhang N, Ness KK, Stokes DC, Krasin MT, Fowler JA, Robison LL, Hudson MM, Green DM
Increased tricuspid regurgitant jet velocity by Doppler echocardiography in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Feb 20;31;774-81 — 2013 Feb 20 — 774-81
Pulmonary hypertensive vasculopathy following tandem autologous transplantation in pediatric patients with central nervous system tumors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013 Feb;19;235-9 — 2013 Feb — 235-9
Pulmonary arterial occlusive disease following chemotherapy and bone marrow transplantation for leukaemia.
European journal of pediatrics 2002 May;161;247-9 — 2002 May — 247-9