The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.g

Cardiomyopathy (acute, subacute, chronic)

Review at PMID 23540741

Publications

Yuki D, Okura Y, Takayama T, Kawasaki T, Kanbayashi C, Sato N

A case of chemoradiotherapy-associated cardiotoxicity that developed into acute heart failure with progressive subendocardial fibrosis.

Journal of cardiology cases 2014 Sep;10;115-120 — 2014 Sep — 115-120

Lipshultz SE, Cochran TR, Franco VI, Miller TL

Treatment-related cardiotoxicity in survivors of childhood cancer.

Nature reviews. Clinical oncology 2013 Dec;10;697-710 — 2013 Dec — 697-710

Maxwell CB, Jenkins AT

Drug-induced heart failure.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2011 Oct 01;68;1791-804 — 2011 Oct 01 — 1791-804

Morgan C, Tillett T, Braybrooke J, Ajithkumar T

Management of uncommon chemotherapy-induced emergencies.

The Lancet. Oncology 2011 Aug;12;806-14 — 2011 Aug — 806-14