The Drug-Induced Respiratory Disease Website and App

Gases

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Balte PP, Clark KA, Mohr LC, Karmaus WJ, Van Sickle D, Svendsen ER

The Immediate Pulmonary Disease Pattern following Exposure to High Concentrations of Chlorine Gas.

Pulmonary medicine 2013;2013;325869 — 2013 — 325869

Jo JY, Kwon YS, Lee JW, Park JS, Rho BH, Choi WI

Acute respiratory distress due to methane inhalation.

Tuberculosis and respiratory diseases 2013 Mar;74;120-3 — 2013 Mar — 120-3