The Drug-Induced Respiratory Disease Website and App

Radiation therapy, stereotactic (SBRT)

A.k.a. conformational or 3D radiation therapy (Reviews of AEs at PMID 12034601, 26083933, 30402100). Separation of radiation lung injury from cancer relapse or progression may be attempted using serial imaging and 18F PET (PMID 23299492, 23473474, 26083933, 27798931). Imaging at PMID 21623237, 21571656.

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic