Radiation therapy to the breast
Main risk to the lung is organizing pneumonia. Risk to the heart greater with irradiation of left-sided breast tumors. See also under other radiation deliveries and patterns
The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
I - Interstitial/parenchymal lung disease
I.b
Pneumonitis (interstitial lung disease/ILD)
I.c
Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
I.d
Organizing pneumonia pattern (an area or areas of consolidation on imaging)
I.h
Subclinical pulmonary infiltrates/ILD
I.o
Focal/localized area of pneumonitis/fibrosis
I.u
Relapsing or migrating pneumonitis/pneumonia (see also Id)
I.v
Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence
I.z
An area or areas of consolidation