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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Excipients, erroneously/deliberately administered i.v.

5

VI.e Fat/oil embolism - The FES embolism syndrome

2
Last update : 07/05/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Crospovidone
2
Excipients-Vehicle-Preservatives (of drugs)
5
Oil-/lipid-based formulations (parenteral)
3
Talc (inhaled, sniffed, i.v., intrapleural)
3

Publications

Accidental, intravenous infusion of a peanut oil-based medication.
Journal of toxicology. Clinical toxicology 1998;36;733-6 1998

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