Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website and App

Methamphetamine

Met/Meth is an abused drug/substance. Manufacture of met in so-called meth-labs can injure bystanders, family, children, law officers, coroners, firemen and/or forensic people. See also under amphetamine and PMID: 10408124, 16438482, 1758482, 18166274, 19936975, 9358986, 21683529. When cut with talc, methamphetamine can cause pneumoconiosis and PMF (PMID 23050878). Examination of the oral cavity for meth-mouth is indicated (PMID 21874893, 25662544). Management issues at PMID 25724076. Meth is sometimes carried by body-packers (PMID 19342282)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I - Interstitial/parenchymal lung disease

II - Pulmonary edema - Acute lung injury - ARDS

III - Pulmonary/alveolar./airway hemorrhage/bleeding

IV - Airway involvement

V - Central-large-upper airway (incl. pharyngeal-nasal) involvement

VII - Pulmonary vasculopathy

VIII - Mediastinal involvement

IX - Neuromuscular / CNS involvement - Disordered breathing (during sleep)

X - Systemic/Distant conditions, syndromes and reactions

XI - Miscellaneous

XII - Cardiovascular involvement / toxicity

XIX - Pathology