The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVII.h

Pneumomediastinum

Publications

Agustin M, David G, Kang JY, Teerasukjinda O

Spontaneous Pneumomediastinum and Diffuse Subcutaneous Emphysema after Methamphetamine Inhalation.

Case reports in pulmonology 2020;2020;7538748 — 2020 — 7538748

Pourmotabed S, Jalili M

Pneumomediastinum following Crystal Use: A Report of Two Cases.

Case reports in emergency medicine 2016;2016;9730484 — 2016 — 9730484

Iyer VN, Joshi AY, Ryu JH

Spontaneous pneumomediastinum: analysis of 62 consecutive adult patients.

Mayo Clinic proceedings 2009 May;84;417-21 — 2009 May — 417-21