The Drug-Induced Respiratory Disease Website and App

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Makker R, Mishra P, Ahuja K

Anaphylaxis spares no drug: A report of diclofenac-induced anaphylaxis mimicking post-laparoscopy respiratory complication.

Saudi journal of anaesthesia 2023;17;236-238 — 2023 — 236-238

Dhopeshwarkar N, Sheikh A, Doan R, Topaz M, Bates DW, Blumenthal KG, Zhou L

Drug-Induced Anaphylaxis Documented in Electronic Health Records.

The journal of allergy and clinical immunology. In practice 2019 Jan;7;103-111 — 2019 Jan — 103-111

Goh SH, Soh JY, Loh W, Lee KP, Tan SC, Heng WJK, Ibrahim I, Lee BW, Chiang WC

Cause and Clinical Presentation of Anaphylaxis in Singapore: From Infancy to Old Age.

International archives of allergy and immunology 2018;175;91-98 — 2018 — 91-98

Aun MV, Blanca M, Garro LS, Ribeiro MR, Kalil J, Motta AA, Castells M, Giavina-Bianchi P

Nonsteroidal anti-inflammatory drugs are major causes of drug-induced anaphylaxis.

The journal of allergy and clinical immunology. In practice 2014 Jul-Aug;2;414-20 — 2014 Jul-Aug — 414-20

Khan NU, Shakeel N, Makda A, Mallick AS, Ali Memon M, Hashmi SH, Khan UR, Razzak JA

Anaphylaxis: incidence, presentation, causes and outcome in patients in a tertiary-care hospital in Karachi, Pakistan.

QJM : monthly journal of the Association of Physicians 2013 Dec;106;1095-101 — 2013 Dec — 1095-101

Brown SG, Stone SF, Fatovich DM, Burrows SA, Holdgate A, Celenza A, Coulson A, Hartnett L, Nagree Y, Cotterell C, Isbister GK

Anaphylaxis: clinical patterns, mediator release, and severity.

The Journal of allergy and clinical immunology 2013 Nov;132;1141-1149.e5 — 2013 Nov — 1141-1149.e5

Renaudin JM, Beaudouin E, Ponvert C, Demoly P, Moneret-Vautrin DA

Severe drug-induced anaphylaxis: analysis of 333 cases recorded by the Allergy Vigilance Network from 2002 to 2010.

Allergy 2013 Jul;68;929-37 — 2013 Jul — 929-37

Solé D, Ivancevich JC, Borges MS, Coelho MA, Rosário NA, Ardusso L, Bernd LA,

Anaphylaxis in Latin American children and adolescents: the Online Latin American Survey on Anaphylaxis (OLASA).

Allergologia et immunopathologia 2012 Nov-Dec;40;331-5 — 2012 Nov-Dec — 331-5

Webb LM, Lieberman P

Anaphylaxis: a review of 601 cases.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006 Jul;97;39-43 — 2006 Jul — 39-43

Quiralte J, Delgado J, Sáenz de San Pedro B, López-Pascual E, Nieto MA, Ortega N, Florido JF, Conde J

Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004 Oct;93;360-4 — 2004 Oct — 360-4

Mullins RJ

Anaphylaxis: risk factors for recurrence.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003 Aug;33;1033-40 — 2003 Aug — 1033-40

Levy M

Hypersensitivity to pyrazolones.

Thorax 2000 Oct;55 Suppl 2;S72-4 — 2000 Oct — S72-4

Kemp SF, Lockey RF, Wolf BL, Lieberman P

Anaphylaxis. A review of 266 cases.

Archives of internal medicine 1995 Sep 11;155;1749-54 — 1995 Sep 11 — 1749-54