The Drug-Induced Respiratory Disease Website and App

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.a

DRES syndrome - DRESS-like reaction

Publications

Nam YH, Park MR, Nam HJ, Lee SK, Kim KH, Roh MS, Um SJ, Son CH

Drug reaction with eosinophilia and systemic symptoms syndrome is not uncommon and shows better clinical outcome than generally recognised.

Allergologia et immunopathologia 2015 Jan-Feb;43;19-24 — 2015 Jan-Feb — 19-24

Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L, Roujeau JC

The DRESS syndrome: a literature review.

The American journal of medicine 2011 Jul;124;588-97 — 2011 Jul — 588-97

Um SJ, Lee SK, Kim YH, Kim KH, Son CH, Roh MS, Lee MK

Clinical features of drug-induced hypersensitivity syndrome in 38 patients.

Journal of investigational allergology & clinical immunology 2010;20;556-62 — 2010 — 556-62

Kucharewicz I, Kemona-Chetnik I, Reduta T, Wierzbicka I, Flisiak R, Bodzenta-Lukaszyk A

Drug rash with eosinophilia and systemic symptoms after ibuprofen intake.

Journal of investigational allergology & clinical immunology 2007;17;347-8 — 2007 — 347-8