The Drug-Induced Respiratory Disease Website and App

Corticosteroids, systemic (oral, parenteral)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IX.v

Generalized myopathy/muscle weakness

Publications

Teagarden CM, Picardo CW

Betamethasone-induced hypokalemic periodic paralysis in pregnancy.

Obstetrics and gynecology. 2011;117(2 Pt 2):433-435

Deem S

Intensive-care-unit-acquired muscle weakness.

Respiratory care. 2006;51(9):1042-52; discussion 1052-3

Nava S, Fracchia C, Callegari G, Ambrosino N, Barbarito N, Felicetti G

Weakness of respiratory and skeletal muscles after a short course of steroids in patients with acute lung rejection.

The European respiratory journal. 2002;20(2):497-9