The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Generalized myopathy/muscle weakness
Publications
Betamethasone-induced hypokalemic periodic paralysis in pregnancy.
Obstetrics and gynecology 2011 Feb;117;433-5 — 2011 Feb — 433-5
Intensive-care-unit-acquired muscle weakness.
Respiratory care 2006 Sep;51;1042-52; discussion 1052-3 — 2006 Sep — 1042-52; discussion 1052-3
Weakness of respiratory and skeletal muscles after a short course of steroids in patients with acute lung rejection.
The European respiratory journal 2002 Aug;20;497-9 — 2002 Aug — 497-9