The Drug-Induced Respiratory Disease Website and App

Corticosteroids, systemic (oral, parenteral)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

L.ad

Vertebral compression fracture

Publications

Balasubramanian A, Wade SW, Adler RA, Saag K, Pannacciulli N, Curtis JR

Glucocorticoid Exposure and Fracture Risk in a Cohort of US Patients With Selected Conditions.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2018 Oct;33;1881-1888 — 2018 Oct — 1881-1888

Jaramillo JD, Wilson C, Stinson DS, Lynch DA, Bowler RP, Lutz S, Bon JM, Arnold B, McDonald ML, Washko GR, Wan ES, DeMeo DL, Foreman MG, Soler X, Lindsay SE, Lane NE, Genant HK, Silverman EK, Hokanson JE, Make BJ, Crapo JD, Regan EA,

Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk.

Annals of the American Thoracic Society 2015 May;12;648-56 — 2015 May — 648-56

Leech JA, Dulberg C, Kellie S, Pattee L, Gay J

Relationship of lung function to severity of osteoporosis in women.

The American review of respiratory disease 1990 Jan;141;68-71 — 1990 Jan — 68-71