The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.ac

Acute radiation pneumonitis

Publications

Leprieur EG, Fernandez D, Chatellier G, Klotz S, Giraud P, Durdux C

Acute radiation pneumonitis after conformational radiotherapy for nonsmall cell lung cancer: clinical, dosimetric, and associated-treatment risk factors.

Journal of cancer research and therapeutics. 2013;9(3):447-51

Ghafoori P, Marks LB, Vujaskovic Z, Kelsey CR

Radiation-induced lung injury. Assessment, management, and prevention.

Oncology (Williston Park, N.Y.). 2008;22(1):37-47; discussion 52-3

Sekine I, Sumi M, Ito Y, Nokihara H, Yamamoto N, Kunitoh H, Ohe Y, Kodama T, Saijo N, Tamura T

Retrospective analysis of steroid therapy for radiation-induced lung injury in lung cancer patients.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2006;80(1):93-7

Roswit B, White DC

Severe radiation injuries of the lung.

AJR. American journal of roentgenology. 1977;129(1):127-36