The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Hosono Y, Sawa N, Nakatsubo S, Ishijima M, Uenami T, Kanazu M, Akazawa Y, Yano Y, Mori M, Yamaguchi T, Yokota S

Radiation Pneumonitis with Eosinophilic Alveolitis in a Lung Cancer Patient.

Internal medicine (Tokyo, Japan). 2018;57(9):1281-1285

Nakayasu H, Shirai T, Tanaka Y, Saigusa M

Chronic eosinophilic pneumonia after radiation therapy for squamous cell lung cancer.

Respiratory medicine case reports. 2017;22:147-149

Cottin V, Frognier R, Monnot H, Levy A, DeVuyst P, Cordier JF, Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires

Chronic eosinophilic pneumonia after radiation therapy for breast cancer.

The European respiratory journal. 2004;23(1):9-13