The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VIII.a

Angioedema (may cause UAO, asphyxia and death)

Publications

Wang GS, Hoyte C

Common Substances of Abuse.

Pediatrics in review. 2018;39(8):403-414

Winston A, Kanzy A, Bachuwa G

Air Duster abuse causing rapid airway compromise.

BMJ case reports. 2015;2015

Kurniali PC, Henry L, Kurl R, Meharg JV

Inhalant abuse of computer cleaner manifested as angioedema.

The American journal of emergency medicine. 2012;30(1):265.e3-5

Mattingly G, Rodu B, Alling R

Quincke's disease: nonhereditary angioneurotic edema of the uvula.

Oral surgery, oral medicine, and oral pathology. 1993;75(3):292-5