The Drug-Induced Respiratory Disease Website and App

Corticosteroids, systemic (oral, parenteral)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VII.j

Compression of mediastinal structures/organs

Publications

Bulakci M, Yahyayev A, Ucar A, Erer B, Erer B, Dursun M

Unusual cause of right ventricular outflow tract compression: mediastinal lipomatosis.

Journal of thoracic imaging. 2011;26(4):W134-6

Puttarajappa C, Dhoble A

Mediastinal lipomatosis as a cause of low voltage complexes on electrocardiogram and widened mediastinum: A case report.

Cases journal. 2008;1(1):171

Gombar S, Mitra S, Thapa D, Gombar KK, Pathak R

Anesthetic considerations in steroid-induced mediastinal lipomatosis.

Anesthesia and analgesia. 2004;98(3):862-4, table of contents

Sorhage F, Stover DE, Mortazavi A

Unusual etiology of cough in a woman with asthma.

Chest. 1996;110(3):852-4

Hoskins MC, Evans RA, King SJ, Gishen P

'Sabre sheath' trachea with mediastinal lipomatosis mimicking a mediastinal tumour.

Clinical radiology. 1991;44(6):417-8