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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Laberge L, Pratt M

Immediate and delayed hypersensitivity to systemic corticosteroids: 2 case reports.

Dermatitis : contact, atopic, occupational, drug. 2012;23(6):288-90

Erdmann SM, Abuzahra F, Merk HF, Schroeder A, Baron JM

Anaphylaxis induced by glucocorticoids.

The Journal of the American Board of Family Practice. 2005;18(2):143-6

Nakamura H, Matsuse H, Obase Y, Mitsuta K, Tomari S, Saeki S, Kawano T, Kondo Y, Machida I, Shimoda T, Asai S, Kohno S

Clinical evaluation of anaphylactic reactions to intravenous corticosteroids in adult asthmatics.

Respiration; international review of thoracic diseases. 2002;69(4):309-13

Laine-Cessac P, Moshinaly H, Gouello JP, Geslin P, Allain P

[Severe anaphylactoid reactions after intravenous corticosteroids. Report of a case and review of the literature].

Therapie. 1990;45(6):505-8

Murrieta-Aguttes M, Michelen V, Leynadier F, Duarte-Risselin C, Halpern GM, Dry J

Systemic allergic reactions to corticosteroids.

The Journal of asthma : official journal of the Association for the Care of Asthma. 1991;28(5):329-39