The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
ARDS - Acute lung injury
Publications
Radiation pneumonitis; clinicopathological exercises.
The New England journal of medicine 1945 Nov 15;233;597-601 — 1945 Nov 15 — 597-601
Radiographic appearance of the chest following extended field radiation therapy for Hodgkin's disease. A consideration of time-dose relationships.
Cancer 1973 Jul;32;206-15 — 1973 Jul — 206-15
The association of adult respiratory distress syndrome (ARDS) with thoracic irradiation (RT).
International journal of radiation oncology, biology, physics 1988 Dec;15;1441-6 — 1988 Dec — 1441-6