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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XV.bh

Path: Foreign body reaction in large airway walls

Last update : 01/01/1970
 

Causative drugs

1

Alendronate - Alendronic acid

IV.s IV - Airway involvement
IV.s - Lolalized airway inflammation/burgeoning/stenosis: The pill aspiration syndrome
VIII.d VIII - Central-large-upper airway (incl. pharyngeal-nasal) involvement
VIII.d - Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway
VIII.ad VIII - Central-large-upper airway (incl. pharyngeal-nasal) involvement
VIII.ad - Osteonecrosis of the jaw
X.b X - Systemic/Distant conditions, syndromes and reactions
X.b - Antiphospholipid antibodies w/wo the APL syndrome
XI.i XI - Miscellaneous
XI.i - Esophageal toxicity
XI.o XI - Miscellaneous
XI.o - Dysphagia
XV.bh XV - Pathology
XV.bh - Path: Foreign body reaction in large airway walls
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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