The Drug-Induced Respiratory Disease Website and App

Status post-thoracic/cardiovascular surgery

Antecedent thoracic (incl. resectional) and/or acrdiovascular surgery. Including, but not limited to CABG can be associated with a plethora of early, middterm and/or late mechanical pulmonary, pleural or neuromuscular complications. Pneumonectomy is known to induce the specific complications listed under XIaa, ab. Reviews at PMID 11796900, 16973775, 21546734

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic