The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleural effusion (uni- or bilateral) (can accompany DI-LDs)
Publications
Light RW, Rogers JT, Moyers JP, Lee YC, Rodriguez RM, Alford WC, Ball SK, Burrus GR, Coltharp WH, Glassford DM, Hoff SJ, Lea JW, Nesbitt JC, Petracek MR, Starkey TD, Stoney WS, Tedder M
Prevalence and clinical course of pleural effusions at 30 days after coronary artery and cardiac surgery.
American journal of respiratory and critical care medicine 2002 Dec 15;166;1567-71 — 2002 Dec 15 — 1567-71
Symptomatic persistent post-coronary artery bypass graft pleural effusions requiring operative treatment : clinical and histologic features.
Chest 2001 Mar;119;795-800 — 2001 Mar — 795-800