The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Progression, acceleration or exacerbation of preexisting ILD/fibrosis
Publications
Sato T, Teramukai S, Kondo H, Watanabe A, Ebina M, Kishi K, Fujii Y, Mitsudomi T, Yoshimura M, Maniwa T, Suzuki K, Kataoka K, Sugiyama Y, Kondo T, Date H, Japanese Association for Chest Surgery
Impact and predictors of acute exacerbation of interstitial lung diseases after pulmonary resection for lung cancer.
The Journal of thoracic and cardiovascular surgery. 2014;147(5):1604-1611.e3
Lung surgery in interstitial lung disease-a safe and useful procedure?
Journal of thoracic disease. 2013;5(4):375-7
Postoperative Acute Exacerbation of IPF after Lung Resection for Primary Lung Cancer.
Pulmonary medicine. 2011;2011:960316