Philippe Camus, M.D.

Dijon, France

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Chemical weapons

Presentation can include acute respiratory failure of neuromuscular origin. Recent cases pointing to the use of Novichok agent(s) indicate the need for pulmonary and emergency physicians to be aware and knowledgeable about these agents and their effects in humans. See PMID 29694809, 29757015, 30003185, 30608256

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

No patterns are linked to this drug.