Osimertinib
Specialities: Oncology · Thoracic oncology
The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
I - Interstitial/parenchymal lung disease
I.a
Pneumonitis (ILD), acute and/or severe (may produce the ARDS pattern)
I.b
Pneumonitis (interstitial lung disease/ILD)
I.c
Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
I.h
Subclinical pulmonary infiltrates/ILD
I.ad
Radiation recall pneumonitis
I.av
Transient pulmonary opacities/infiltrates (TAPO) (see also under IIj)
I.az
Pulmonary alveolar proteinosis flare/exacerbation