Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website and App

Oil-/lipid-based formulations (parenteral)

Drugs injected IM, intradermally or (rarely IV) as oil-based formulations or oil/lipid depots, particularly sexual/anabolic steroids. To quote Meyer & Mann 2015 (PMID PMID 25686650), *well described in on-line chat rooms related to the use of anabolic steroids in body building". Synthol as used by bodybuilders exposes to similar risks (PMID 19580174)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic