The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.ab

Cough (lone)

No statistical evidence found, however (PMID 31980869)

Publications

Dicpinigaitis P, Satia I, Ferguson N

Falsely Accused? Insufficient Evidence to Conclude that Sitagliptin is a Cause of Chronic Cough.

Lung 2020 Jan 24;; — 2020 Jan 24

Baraniuk JN, Jamieson MJ

Rhinorrhea, cough and fatigue in patients taking sitagliptin.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2010 May 12;6;8 — 2010 May 12 — 8