The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
ARDS - Acute lung injury
Publications
Acute respiratory distress syndrome after airway anesthesia with lidocaine.
Journal of bronchology & interventional pulmonology 2010 Jul;17;245-7 — 2010 Jul — 245-7
[Adult respiratory distress syndrome (ARDS) after poisoning by local anesthetics].
Schweizerische medizinische Wochenschrift 1982 Nov 20;112;1710-3 — 1982 Nov 20 — 1710-3
Adult respiratory distress syndrome following administration of lidocaine.
Chest 1982 May;81;644-5 — 1982 May — 644-5
Death from ARDS and cardiovascular collapse following lidocaine administration.
Chest 1983 Mar;83;585 — 1983 Mar — 585