The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.e

Organizing pneumonia pattern (an area or areas of consolidation on imaging)

Publications

Lee EJ, Lee SY, In KH, Kim CH, Park S

Organizing pneumonia associated with oxaliplatin-combined chemotherapy: a case report.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2012;21;89-92 — 2012 — 89-92

Fekrazad MH, Eberhardt S, Jones DV, Lee FC

Development of bronchiolitis obliterans organizing pneumonia with platinum-based chemotherapy for metastatic rectal cancer.

Clinical colorectal cancer 2010 Jul;9;177-8 — 2010 Jul — 177-8

Garrido M, O'Brien A, González S, Clavero JM, Orellana E

Cryptogenic organizing pneumonitis during oxaliplatin chemotherapy for colorectal cancer: case report.

Chest 2007 Dec;132;1997-9 — 2007 Dec — 1997-9