The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Makker R, Mishra P, Ahuja K

Anaphylaxis spares no drug: A report of diclofenac-induced anaphylaxis mimicking post-laparoscopy respiratory complication.

Saudi journal of anaesthesia 2023;17;236-238 — 2023 — 236-238

Picaud J, Beaudouin E, Renaudin JM, Pirson F, Metz-Favre C, Dron-Gonzalvez M, Moneret-Vautrin DA

Anaphylaxis to diclofenac: nine cases reported to the Allergy Vigilance Network in France.

Allergy 2014 Oct;69;1420-3 — 2014 Oct — 1420-3

Chaudhry T, Hissaria P, Wiese M, Heddle R, Kette F, Smith WB

Oral drug challenges in non-steroidal anti-inflammatory drug-induced urticaria, angioedema and anaphylaxis.

Internal medicine journal 2012 Jun;42;665-71 — 2012 Jun — 665-71

Singh R, Bansal D, Baduni N, Vajifdar H

Anaphylactic reaction to intravenous diclofenac.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 2011 Jan;15;37-9 — 2011 Jan — 37-9

de Groot JW, Gosselink AT, Ottervanger JP

Acute ST-segment elevation myocardial infarction associated with diclofenac-induced anaphylaxis: case report.

American journal of critical care : an official publication, American Association of Critical-Care Nurses 2009 Jul;18;388, 386-7 — 2009 Jul — 388, 386-7

Leone R, Conforti A, Venegoni M, Motola D, Moretti U, Meneghelli I, Cocci A, Sangiorgi Cellini G, Scotto S, Montanaro N, Velo G

Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.

Drug safety 2005;28;547-56 — 2005 — 547-56

van der Klauw MM, Stricker BH, Herings RM, Cost WS, Valkenburg HA, Wilson JH

A population based case-cohort study of drug-induced anaphylaxis.

British journal of clinical pharmacology 1993 Apr;35;400-8 — 1993 Apr — 400-8