The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIV.a

Angioedema (may cause UAO, asphyxia and death)

Publications

Strassen U, Bas M, Hoffmann TK, Knopf A, Greve J

Treatment of angiotensin receptor blocker-induced angioedema: A case series.

The Laryngoscope 2015 Jul;125;1619-23 — 2015 Jul — 1619-23

Gabb G, Andrew N

Lump in the throat - a case study.

Australian family physician 2013 Dec;42;863-6 — 2013 Dec — 863-6

Hamasaki H, Hiraishi C, Yanai H

Severe angioedema induced by angiotensin II receptor blocker.

International journal of cardiology 2013 Sep 20;168;e15-6 — 2013 Sep 20 — e15-6

Taki M, Watanabe H, Hasegawa T, Bamba H, Shimada T, Hisa Y

Angioedema: 6 years experience with fourteen cases.

Auris, nasus, larynx 2010 Apr;37;199-204 — 2010 Apr — 199-204

Adachi YU, Iwakiri S, Katoh T

Angioedema, angiotensin converting enzyme inhibitors, and angiotensin receptor blocking drugs.

Canadian journal of anaesthesia = Journal canadien d'anesthesie 2007 Feb;54;155-7; author reply 157 — 2007 Feb — 155-7; author reply 157

Lo KS

Angioedema associated with candesartan.

Pharmacotherapy 2002 Sep;22;1176-9 — 2002 Sep — 1176-9