The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LV.v

Imaging: Centrilobular micronodules (can be diffuse)

Publications

Rizos ED, Antonogiannaki EM, Chatzidakis A, Kallieri M, Tsilogianni Z, Manali ED, Economopoulos N, Triantafyllou K, Papiris SA, Polymeros D

Vedolizumab-induced acute interstitial lung injury in a 39-year-old male with ulcerative colitis.

European journal of gastroenterology & hepatology 2021 May 31;; — 2021 May 31