The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary edema, noncardiogenic (NCPE)
Publications
Pulmonary edema associated with hyperbaric oxygen therapy.
Chest. 2001;120(4):1407-9
Pulmonary lesions associated with oxygen therapy and artificial ventilation.
The New England journal of medicine. 1967;276(7):368-74
Oxygen toxicity in man. A prospective study in patients with irreversible brain damage.
The New England journal of medicine. 1970;283(27):1478-84