The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.m

Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

Publications

Pontes LB, Armentano DP, Soares A, Gansl RC

Fatal pneumonitis induced by oxaliplatin: description of three cases.

Case reports in oncology 2012 Jan;5;104-9 — 2012 Jan — 104-9

Watkins J, Slade JH, Phan A, Eng C, Weissferdt A, Overman MJ

Fatal diffuse alveolar damage associated with oxaliplatin administration.

Clinical colorectal cancer 2011 Sep;10;198-202 — 2011 Sep — 198-202