The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.g

Pulmonary fibrosis

Publications

Ryu CG, Jung EJ, Kim G, Kim SR, Hwang DY

Oxaliplatin-induced Pulmonary Fibrosis: Two Case Reports.

Journal of the Korean Society of Coloproctology 2011 Oct;27;266-9 — 2011 Oct — 266-9

Arévalo Lobera S, Sagastibeltza Mariñelarena N, Elejoste Echeberría I, Melé Olivé M, Egaña Otaño L, Basterretxea Badiola L, La Casta Muñoa A, Azkue Gabilondo M

Fatal pneumonitis induced by oxaliplatin.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2008 Nov;10;764-7 — 2008 Nov — 764-7