The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Khan AM, Jariwala S, Lieman HJ, Klapper P

Acute eosinophilic pneumonia with intramuscular progesterone after in vitro fertilization.

Fertility and sterility 2008 Oct;90;1200.e3-6 — 2008 Oct — 1200.e3-6

Veysman B, Vlahos I, Oshva L

Pneumonitis and eosinophilia after in vitro fertilization treatment.

Annals of emergency medicine 2006 May;47;472-5 — 2006 May — 472-5

Bouckaert Y, Robert F, Englert Y, De Backer D, De Vuyst P, Delbaere A

Acute eosinophilic pneumonia associated with intramuscular administration of progesterone as luteal phase support after IVF: case report.

Human reproduction (Oxford, England) 2004 Aug;19;1806-10 — 2004 Aug — 1806-10

Phy JL, Weiss WT, Weiler CR, Damario MA

Hypersensitivity to progesterone-in-oil after in vitro fertilization and embryo transfer.

Fertility and sterility 2003 Nov;80;1272-5 — 2003 Nov — 1272-5