The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.af

Calcification of tracheobronchial cartilaginous rings

Publications

Kansara T, Tornay J, Agarwal S

Warfarin-Associated Tracheobronchial Calcification.

American journal of therapeutics. 2019;26(6):e787-e788

Nigwekar SU, Thadhani R, Brandenburg VM

Calciphylaxis.

The New England journal of medicine. 2018;378(18):1704-1714

Nour SA, Nour HA, Mehta J, Roy T, Byrd R

Tracheobronchial calcification due to warfarin therapy.

American journal of respiratory and critical care medicine. 2014;189(12):e73

Eckersley L, Stirling J, Occleshaw C, Wilson N

Two cases of warfarin-induced tracheobronchial calcification after Fontan surgery.

Pediatric cardiology. 2014;35(6):954-8

Thoongsuwan N, Stern EJ

Warfarin-induced tracheobronchial calcification.

Journal of thoracic imaging. 2003;18(2):110-2

Joshi A, Berdon WE, Ruzal-Shapiro C, Barst RJ

CT detection of tracheobronchial calcification in an 18-year-old on maintenance warfarin sodium therapy: cause and effect?

AJR. American journal of roentgenology. 2000;175(3):921-2

Moncada RM, Venta LA, Venta ER, Fareed J, Walenga JM, Messmore HL

Tracheal and bronchial cartilaginous rings: warfarin sodium-induced calcification.

Radiology. 1992;184(2):437-9