The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Perforation of the heart - Cardiac rupture
Publications
Case report: Inspiration from a rare fatal heart perforation after percutaneous vertebroplasty.
Frontiers in surgery 2023;10;1227056 — 2023 — 1227056
Fatal cardiac perforation and pulmonary embolism of leaked cement after percutaneous vertebroplasty.
Journal of forensic and legal medicine 2019 Apr;63;48-51 — 2019 Apr — 48-51