The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Furukawa S, Takaya A, Nakagawa T, Sakaguchi I, Nishi K

Fatal hypernatremia due to drinking a large quantity of shoyu (Japanese soy sauce).

Journal of forensic and legal medicine 2011 Feb;18;91-2 — 2011 Feb — 91-2

Paut O, André N, Fabre P, Sobraquès P, Drouet G, Arditti J, Camboulives J

The management of extreme hypernatraemia secondary to salt poisoning in an infant.

Paediatric anaesthesia 1999;9;171-4 — 1999 — 171-4