The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVIII.b

BAL: An excess proportion of neutrophils

Publications

Horibe R, Hashimoto M, Nishiyama K

Bronchiolitis of immune checkpoint inhibitor therapy-related pneumonitis.

The American journal of the medical sciences 2022 Sep 23;; — 2022 Sep 23

Sehgal S, Velcheti V, Mukhopadhyay S, Stoller JK

Focal lung infiltrate complicating PD-1 inhibitor use: A new pattern of drug-associated lung toxicity?

Respiratory medicine case reports 2016;19;118-20 — 2016 — 118-20