The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIII.a

Bronchospasm - Wheezing - Asthma

Publications

Nakamura N, Tamagawa-Mineoka R, Masuda K, Katoh N

Immediate-type allergic reactions to local anesthetics.

Allergology international : official journal of the Japanese Society of Allergology 2018 Jan;67;160-161 — 2018 Jan — 160-161

van der Bijl P, Broeksma J

Acute bronchospasm following administration of lidocaine.

Anesthesia & pain control in dentistry 1993;2;203-5 — 1993 — 203-5