The Drug-Induced Respiratory Disease Website and App

Immune checkpoint inhibitors (ICI) - ICI combinatorial Rx

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.d

Lupus - Lupus syndrome (see also Vd)

Publications

Raschi E, Antonazzo IC, Poluzzi E, De Ponti F

Drug-induced systemic lupus erythematosus: should immune checkpoint inhibitors be added to the evolving list?

Annals of the rheumatic diseases 2019 Jun 12;; — 2019 Jun 12

de Chabot G, Justeau G, Pinquié F, Nadaj-Pakleza A, Hoppé E, Hureaux J, Urban T

[Unexpected adverse events of immunotherapies in non-small cell lung cancer: About 2 cases].

Revue de pneumologie clinique 2017 Dec;73;326-330 — 2017 Dec — 326-330

Abdel-Wahab N, Shah M, Suarez-Almazor ME

Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports.

PloS one 2016;11;e0160221 — 2016 — e0160221