The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LV.ad

Imaging: Lung cysts or bullae (see also XVI ah/bf)

Publications

Gorospe L, Ayala-Carbonero AM, Olmedo-García ME, Gómez-Rueda A, Palka M, Mezquita L, Garrido-López P

Nivolumab-induced pneumonitis complicated by cyst formation.

Lung cancer (Amsterdam, Netherlands) 2018 08;122;258-259 — 2018 08 — 258-259

Rampinelli C, Spitaleri G, Passaro A, Pochesci A, Ancona E, De Marinis F

Lung Tissue Injury as an Atypical Response to Nivolumab in Non-Small Cell Lung Cancer.

American journal of respiratory and critical care medicine 2017 Nov 15;196;1349-1350 — 2017 Nov 15 — 1349-1350