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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Na W, Wang Y, Li A, Zhu X, Xue C, Ye Q

Acute chlorine poisoning caused by an accident at a swimming pool.

Toxicology and industrial health. 2021;37(9):513-519

Fronczek J, Gilbert JD, Byard RW

Forensic issues arising in the assessment of chlorine-related deaths in a domestic setting.

Medicine, science, and the law. 2021;61(3):232-235

Cordasco EM, Stone FD

Pulmonary edema of environmental origin.

Chest. 1973;64(2):182-5