The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLII.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Reddy JC, Shuman MA, Aster RH

Quinine/quinidine-induced thrombocytopenia: a great imitator.

Archives of internal medicine 2004 Jan 26;164;218-20 — 2004 Jan 26 — 218-20

LeBlanc KE

A second case of quinidine-induced thrombocytopenia with pulmonary hemorrhage.

Archives of internal medicine 1980 Sep;140;1250-1 — 1980 Sep — 1250-1

Alperin JB, deGroot WJ, Cimo PL

Quinidine-induced thrombocytopenia with pulmonary hemorrhage.

Archives of internal medicine 1980 Feb;140;266-7 — 1980 Feb — 266-7