The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XV.c

Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

Publications

Nelson BE, Hong A, Okereke I, Markowitz A, Willis M, Muthukumarana PV, Nawgiri R

Non-neoplastic inflammatory pseudotumor of the lung after immunotherapy for melanoma: A diagnostic pitfall on fine needle aspiration biopsy of lung.

Diagnostic cytopathology. 2021;49(10):1150-1154

Costa JM, Carvalho SD, Soares JB

Mesalazine-induced Bronchiolitis Obliterans With Organising Pneumonia in a Young Patient With Ulcerative Colitis.

Journal of Crohn's & colitis. 2018;12(11):1377-1378

Mahjoubi L, Gazzah A, Marabelle A, Le Roy Ladurie F, Lambotte O, Caramella C, Adam J, Besse B, Soria JC

Late-occurring nivolumab-induced cryptogenic organising pneumonia mimicking lung progression in a patient with metastatic non-small cell lung cancer.

European journal of cancer (Oxford, England : 1990). 2017;85:155-157

Kiyohara Y, Yoshikawa S, Otsuka M, Kondou R, Iizuka A, Nonomura C, Ohshima K, Urakami K, Kusuhara M, Nagashima T, Sugino T, Yamaguchi K, Akiyama Y

Melanoma patient response to nivolumab treatment for metastatic lung lesions: Multi-OMICS analysis in Project HOPE.

The Journal of dermatology. 2017;44(10):1156-1159

Sano T, Uhara H, Mikoshiba Y, Kobayashi A, Uchiyama R, Tateishi K, Yamamoto H, Okuyama R

Nivolumab-induced organizing pneumonia in a melanoma patient.

Japanese journal of clinical oncology. 2016;46(3):270-2

Nakashima K, Naito T, Omori S, Yoshikawa S, Endo M, Kiyohara Y, Takahashi T

Organizing Pneumonia Induced by Nivolumab in a Patient with Metastatic Melanoma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016;11(3):432-3